Comparison on Detection Results of Pathogen Nucleic Acids for Bronchoalveolar Lavage Fluid of Lung Infection Infants Between Uighur Nationality and Han Nationality

Linglong Lu (Maternal and Child Health Hospital of Guangdong Province)


Objective: To analyze the detection results of pathogen nucleic acids for bronchoalveolar lavage fluid (BALF) of lung infection infants from Uighur nationality and Han nationality. Methods: A retrospective analysis was performed on the 318 infants with lung infection who were admitted to the hospital from April 2018 to April 2019. According to their nationality, they were divided into Uighur nationality group (190 cases) and Han nationality group (128 cases). The BALF specimens were collected to test pathogen nucleic acid. The distribution and positive rates of [respiratory syncytial virus (RSV), adenovirus (ADV), influenza virus A (IFA), influenza virus B (IFB), parainfluenza virus type 1 (PIV I), parainfluenza virus type 2 (PIV II), parainfluenza virus type 3 (PIV III)], bacteria (Streptococcus pneumoniae, Haemophilus influenzae, staphylococcus aureus, Pseudomonas aeruginosa, klebsiella pneumoniae), Mycoplasma pneumoniae (MP) and Chlamydia pneumoniae (CP) in both groups were observed and compared. Results: The virus detection for RSV, ADV and PIV III were on the top three in BALF from the children in both groups. The total positive rate of virus examination in Uighur nationality group was higher than that in Han nationality group (P<0.05). BALF in both groups was mainly on Streptococcus pneumoniae. The total positive rate of bacteria, MP and detection rate of chlamydia were higher in Uighur nationality group were higher than those in Han nationality group (P<0.05). Conclusion: The pathogen nucleic acid examination for bronchoalveolar lavage fluid in infants with lung viral infection is in the majority, mainly on RSV virus infection. The positive rates of virus, bacteria, MP and CP of children in Uighur nationality are high than those in Han nationality.


Lung infection; Infant; Fiber bronchoalveolar lavage fluid; Pathogen; Uighur nationality; Han nationality

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