Therapeutic Effect Observation of Tiotropium Bromide in the Treatment of Overlap Syndrome

Yunchao Huang (Department of Pulmonary and Critical Care Medicine, The Second People’s Hospital of Yunnan Province)
Ting Wang (The First Affiliated Hospital of Kunming Medical University)


Objective: To study the M receptor blocker on inhalation in patients with overlap syndrome (chronic obstructive pulmonary disease and Obstructive sleep apnea syndrome) curative effect analysis. Methods: 25 patients with overlap syndrome as the experimental group, chronic obstructive pulmonary disease patients (30) as control group, patients with overlap syndrome use inhaled tiotropium powder treat 30 days, to observe the changes of pulmonary function, polysomnography, and other indicators after treatment. Results: Overlap syndrome were treated by tiotropium bromide inhalation powder, has improved the pulmonary function, the sleep apnea index and lowest nocturnal oxygen saturation after treatment. Conclusion: tiotropium bromide has a preferable effective in treatment of overlap syndrome, COPD and OSAHS are interacting with each other.


Overlap syndrome; COPD; OSAHS; Tiotropium

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