Effects of Exercise on the Pharmacokinetics of Icariin II in Rats

Xiliang Kong (College of Physical Education, Qufu Normal University)


High performance liquid chromatography (HPLC) was established to determine the concentration of Icariin II in rats. The time-dependent changes in rats after taking Icariin II were studied, and the main pharmacokinetic parameters were obtained. The main pharmacokinetic parameters of taking the medicine in a quiet state, taking the medicine after half an hour of exercise and taking the medicine after long-term exercise were compared to verify whether the absorption and utilization of the Icariin II were more favorable in the exercise state; The paper has important guiding significance for guiding athletes to safe medication and further development of this drug.


Icariin II; Exercise state; High performance liquid chromatography

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DOI: https://doi.org/10.30564/jams.v2i1.161


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