Myocardial Protective Effect of Gas Signal Molecule Hydrogen Sulfide on Cardiovascular Disease

Lijuan Li (Medical College of Three Gorges University)
Fei Zou (Medical College of Three Gorges University)


Cardiovascular diseases increase continually in the worldwide scale, and its specific pathogenesis has not been completely clear. The gas signal molecule hydrogen sulfide (H2S) is a new type of neuroactive substance, which plays many biological roles in many systems such as cardiovascular system. In recent years, a lot of research has confirmed H2S has myocardial protective effect on cardiovascular diseases such as atherosclerosis, ischemia-reperfusion injury, hypertension and heart failure. This paper reviews the research status of myocardial protective effect of H2S on cardiovascular diseases.


Hydrogen sulfide; Cardiovascular disease; Atherosclerosis; Ischemia reperfusion injury; High blood pressure; Heart failure

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