Clinical Study of Endovascular Treatment of Severe Middle Cerebral Artery Stenosis or Occlusion and Vascular Cognitive Impairment

Authors

  • Shaojie Yuan Xingtai People’s Hospital
  • Tong Zhang Xingtai People’s Hospital
  • Xiaohui Zhao Xingtai People’s Hospital
  • Liying Yuan Tianjin Fourth Central Hospital
  • Dan Wang Xingtai People’s Hospital

DOI:

https://doi.org/10.30564/jams.v4i2.3339

Abstract

Objective: It is very important to study the factors affecting the incidence, progress and prognosis of patients with vascular dementia.  Methods: 50 cases of severe middle cerebral artery stenosis or occlusion underwent endovascular treatment (25 cases of mild cognitive dysfunction, 25 cases of moderate cognitive dysfunction) were divided into two groups, where a medical drug treatment group and a control group established with 25 cases in each group. The cognitive function of each group of patients was evaluated before operation, 7 days after operation, 30 days after operation, and 180 days after operation. CTP was used to compare the hemodynamic changes in patients before and after operation.  Results: The severe stenosis or occlusion of the middle cerebral artery in patients can be improved, and the intracranial blood supply of patients with poorly compensated medial cranial circulation and hypoperfusion can be restored to a certain extent. Meanwhile, improvement of cognitive function was definitive in some patients with cognitive dysfunction.  Conclusion: To guide the formulation of treatment plans for patients with severe middle cerebral artery stenosis or occlusion.

Keywords:

Acute middle cerebral artery occlusion, Vascular cognitive impairment, Montreal cognitive assessment

References

[1] WANG Yingbin, ZHANG Hao, WANG Huan, WAN Gongshan, GAO Fei. Analysis of prognostic factors influencing endovascular treatment of acute anterior circulation large-vessel occlusive stroke [J/OL]. Journal of China Medical University: 1-7 [2020-11-10].

[2] http://kns.cnki.net/kcms/detail/21.1227.R.20201028.1317.036.html.

[3] WANG Wei, WANG Zanghui, XU Xueling. Subintimal Angioplasty Combined with Cilostazol in the Treatment of Atherosclerosis Obliterans [J]. China Pharmaceuticals, 2020,29(20):61-63.

[4] Zha Mingming, Huang Kangmo, Yang Qingwen, Cai Haodi, Liu Rui, Liu Xinfeng. Influencing factors of excellent prognosis after recanalization for acute anterior circulation large vessel occlusion [J]. Chinese Journal of Cerebrovascular Diseases, 2020, 17(10):569-575.

[5] TAN Lin, LIU Ping, TAN Hui, LI Si-yang, ZHAO Wei-na. Research progress on structural magnetic resonance imaging of non-dementia vascular cognitive impairment [J]. Journal of Mudanjiang Medical University, 2020, 41(05):116-119.

[6] BAI Jin. Clinical effect and prognostic analysis of intravascular interventional treatment of ischemic cerebrovascular disease with severe middle cerebral artery stenosis [J]. China Rural Health, 2020, 12(18):24.

[7] HUANG Mingming, WEI Lin, CAO Xiaowan, FU Xiao, ZENG Bangfeng, YANG Liming, YU Hui, LIU Jing. MRI findings of hippocampal injury in vascular cognitive impairment rat model [J]. Chinese Imaging Journal of Integrated Traditional and Western Medicine,2020, 18(05):435-438.

[8] GUO Yan-kui, CAO Xiao-lan, ZHOU Chen. A study on the correlation between risk factors of vascular cognitive impairment and TCM syndrome factor [J]. Clinical Journal Of Chinese Medicine, 2020, 12(25):8-12.

[9] TAN Yanhuan, LI Junchen, HU Chunhong. Study of Magnetic Resonance Spectroscopy in the Hippocampus in Patients with Vascular Cognitive Impairment no Dementia [J]. Journal of Clinical Radiology, 2020, 39(06):1046-1049.

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