Maternal thyroid hormone is essential for placentation and fetal development. Maternal thyroid dysfunction is then associated with the risk of gestational complications (e.g., preeclampsia and gestational diabetes mellitus) and adverse fetal outcomes, such as fetal growth restriction, preterm birth, brain underdevelopment, and congenital heart defect. However, some associations remain controversial and show specificity for gestational age or variant of thyroid dysfunction.

This themed issue invites original research papers and reviews articles providing More clinical researches to address these concerns, and then providing evidence for clinical decisions.