Leiomyoma Of Urinary Bladder a Rare Entity: Series Of 3 Cases And Review Of Literature

Nitesh Kumar (MS (General Surgery), MCH trainee Urology, Osmania Medical College, India)
Karthik M (MS (General Surgery), MCH trainee Urology, Osmania Medical College, India)
Samyuktha K (MS (General Surgery), MCH trainee Urology, Osmania Medical College, India)
Sunil Palve (MS (General Surgery), MCH trainee Urology, Osmania Medical College, India)
Tushar Agrawal (MS (General Surgery), MCH trainee Urology, Osmania Medical College, India)

Article ID: 1642


Introduction: Leiomyoma of urinary bladder is a rare entity and comprises 0.43% of all bladder tumors. Here we present our series of 3 casesand the related review of literature. Methods: 3 cases of bladder leiomyoma presented over a period of 16 months in Osmania Medical Collegeand Hospital. Detailed history was taken, physical examination, routineblood, urine and radiological investigations were done. Patients weretreated by Trensurethral Resection (TUR) of the mass and histopathological analysis with Immunohistochemistry was done for all cases. Results:All 3 cases were females with mean age of 31.6 years. All cases wereendovesical type, mass near bladder neck and presented with obstructivesymptoms. Two cases presented with acute retention of urine. Radiological investigations in all patients suggested a possibility of leiomyoma andall cases had reduced urinary flow rates. Histopathology confirmed thediagnosis in all cases. No recurrence was found at one year of follow up.Conclusion: Leiomyoma of urinary bladder is a rare disorder which frequently occurs in middle aged females. Symptoms are related to its sizeand location, diagnosis is confirmed by histopathological analysis. Treatment is by surgery (mainly TUR). Prognosis of the disease is excellent.


Leiomyoma; Benign tumor; Bladder outlet obstruction; Benign bladder tumor; LUTS

Full Text:



[1] Khater N, Sakr G. Bladder. leiomyoma: Presentation, evaluation and treatment. Arab journal of urology, 2013, 11(1): 54-61.

[2] Park JW, Jeong BC, Seo SI, Jeon SS, Kwon GY, Lee HM. Leiomyoma of the urinary bladder: a series of nine cases and review of the literature. Urology, 2010, 76(6): 1425-9.

[3] Goluboff ET, O'Toole K, Sawczuk IS. Leiomyoma of bladder: report of case and review of literature. Urology, 1994, 43(2): 238-41.

[4] Campbell EW, Gislason GJ. Benign mesothelial tumors of the urinary bladder: review of literature and a report of a case of leiomyoma. The Journal of urology, 1953, 70(5): 733-42.

[5] Knoll LD, Segura JW, Scheithauer BW. Leiomyoma of the bladder. The Journal of urology, 1986, 136(4): 906-8.

[6] Matsushima M, Asakura H, Sakamoto H, Horinaga M, Nakahira Y, Yanaihara H. Leiomyoma of the bladder presenting as acute urinary retention in a female patient: urodynamic analysis of lower urinary tract symptom; a case report. BMC urology, 2010, 10(1): 13.

[7] Cornella JL, Larson TR, Lee RA, Magrina JF, Kammerer-Doak D. Leiomyoma of the female urethra and bladder: report of twenty-three patients and review of the literature. American journal of obstetrics and gynecology, 1997, 176(6): 1278-85.

[8] Huang HY, Chen WJ, Sung MT, Huang CC. Atypical leiomyoma of the urinary bladder. Scandinavian journal of urology and nephrology, 2002, 36(3): 231-3.

[9] Furuhashi M, Suganuma N. Recurrent bladder leiomyoma with ovarian steroid hormone receptors. The Journal of urology, 2002, 167(3): 1399-400.

[10] Neto AG, Gupta D, Biddle DA, Torres C, Malpica A. Urinary bladder leiomyoma during pregnancy: report of one case with immunohistochemical studies. Journal of Obstetrics and

[11] Gynaecology, 2002, 22(6): 683-5.

[12] Strang A, Lisson SW, Petrou SP. Ureteral endometriosis and coexistent urethral leiomyoma in a postmenopausal woman. International braz j urol, 2004, 30(6): 496-8.

[13] Caspi B, Weinberg D, Weissman A, Eisencraft S, Dgani R. Leiomyosarcoma of the bladder-ultrasonographic features. Ultrasound in Obstetrics and Gynecology: The Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology, 1992, 2(6): 432-3.

[14] Illescas FF, Baker ME, Weinerth JL. Bladder leiomyoma: advantages of sonography over computed tomography. Urologic radiology, 1986, 8(1): 216-8.

[15] Huang C, Luo J, Yuan D, Gan D, Geng K. MRI diagnosis and differential diagnosis of bladder leiomyoma. Journal of Practical Radiology, 2017, 33(8): 1230-2.

[16] Jain S, Dahiya P, Dahiya K, Kamal H, Jain N. Bladder Leiomyoma: A Diagnostic Challenge. Journal of Gynecologic Surgery, 2019.

[17] Puglisi T, Curto F, Caldarella G, Morgia G. Laparoscopic partial bladder cystectomy for a bladder leiomyoma.

[18] Yoshioka T, Kawakita M, Kameoka H. Cystoscope-Assisted Laparoscopic Enucleation of a Large Progressive Bladder Leiomyoma. Journal of Endourology Case Reports, 2019.

[19] Ganapathy VS, Siddappa S, Saini VA, Keshavamurthy R. Bladder Leiomyoma-An Unusual Cause of Acute Urinary Retention. J Cancer Prev Curr Res., 2017, 8(4): 00287.

DOI: https://doi.org/10.30564/jor.v1i3.1642


  • There are currently no refbacks.
Copyright © 2020 Author(s)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.