Progress in diagnosis and treatment of basal cell carcinoma

Yan Liu (Anhui Taihe County People’s Hospital, Taihe, Anhui, 236600, China)
Mengxian Ren (Anhui Taihe County People’s Hospital, Taihe, Anhui, 236600, China)
Youfei Zhao (Anhui Taihe County People’s Hospital, Taihe, Anhui, 236600, China)
Dong Liu (Anhui Taihe County People’s Hospital, Taihe, Anhui, 236600, China)
Fei Zhou (Anhui Taihe County People’s Hospital, Taihe, Anhui, 236600, China)

Article ID: 2038


Basal cell carcinoma is a common skin carcinogenesis that occurs in the epidermis and the basal layer of the general, basal cell carcinoma grows slowly, rarely metastasizes, but is locally invasive and destructive. The diagnosis is based on clinical manifestations, but the clinicopathological manifestations are different, and sometimes it is difficult to differentiate from pigmented nevus, malignant melanoma, etc. Therefore, skin biopsy is essential for the diagnosis and assessment of the risk of recurrence.There are many ways to treat basal cell carcinoma. This article reviews the diagnosis and treatment.


Basal cell carcinoma; Diagnosis and treatment

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[1] Lo J,Snow S,Reizner G.Metastatic basal cell carcinoma:a report of twelve cases with a review of the literature.J Am Acad Dermatol.1991;24:715–9.

[2] Karagas MR,Tosteson TD,Blum J,Morris JS,Baron JA,Klaue B.Design of an epidemiologic study of drinking water arsenic exposure and skin and bladder cancer risk in a U.S.population. Environ Health Perspect.1998;106(Suppl .4):1047-50.

[3] Altamura D, Menzies SW, Argenziano G, Zalaudek I, Soyer HP, Sera F, et al.Dermatoscopy of basal cell carcinoma:morphologic variability of global and local features and accuracy of diagnosis.J Am Acad Dermatol.2010; 62:67–75.

[4] Patterson JW.Weedon's skin pathology.4th ed.London:Churchill-Livingstone;2016.p.806–11.

[5] Sexton M,Jones DB,Maloney ME.Histologic pattern analysis of basal cell carcinoma.Study of a series of 1039consecutive neoplasms.J Am Acad Dermatol.1990;23:1118–26.

[6] Rosai J.Rosai and Ackerman's surgical pathology.9th ed.Edinburgh:Mosby;2004.p.136–9.

[7] Scrivener Y,Grosshans E,Cribier B.Variations of basal cell carcinomas according to gender,age,location and histopathological subtype.Br J Dermatol.2002;147:41–7.

[8] Silverman MK,Kopf AW,Bart RS,Grin CM,Levenstein MS.Recurrence rates of treated basal cell carcinomas.Part 3:surgical excision.J Dermatol Surg Oncol.1992;18:471–6.

[9] Blixt E,Nelsen D,Stratman E.Recurrence rates of aggressive histologic types of basal cell carcinoma after treatment with electrodesiccation and curettage alone.Dermatol Surg.2013;39:719–25.

[10] Geisse J, Caro I, Lindholm J, Golitz L, Stampone P, Owens M.Imiquimod 5%cream for the treatment of superficial basal cell carcinoma:results from two phase III, randomized, vehicle-controlled studies.J Am Acad Dermatol.2004; 50:722–33.

[11] Foley P.Clinical efficacy of methyl aminolevulinate (Metvix) photodynamic therapy. J Dermatolog Treaty .2003;14(Suppl 3):15-22.



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