Research Progress of Anti-tumor Active Ingredients in Dandelion

Jumin Xie (Medical college of Hubei Polytechnic University, Xialu district, Guilinbei Road No 16, Huangshi, Hubei, 435003, China;Hubei key laboratory of renal disease occurrence and intervention, Hubei Polytechnic University, Xialu district, Guilinbei Road No 16, Huangshi, Hubei, 435003, China)
Yudi Huang (Medical college of Hubei Polytechnic University, Xialu district, Guilinbei Road No 16, Huangshi, Hubei, 435003, China)
Qingzhi Wang (Medical college of YiChun University, Xuefu Road No 576, Yichun, Jiangxi, 336000, China)


As a traditional Chinese herb, dandelion, containing complicated activeingredients which includes polysaccharide, flavonoid, terpene, pigment,phytosterol, coumarin, organic acid and etc, plays significant roles invarious physiological activities in organisms. The active ingredientsgenerally interfere in signal transduction of cancer cells, regulate cellcycle and apoptotic protein expression, inhibit cancer cells proliferationand migration and etc, which effectively restrains tumor developmentand deterioration. This article summarizes the anti-tumor mechanism offive active ingredients in dandelion through paper reading which providesthoughts and references for anti-tumor research.


Dandelion;Anti-tumor;Active ingredients

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