Journal of Oncology Research

Abstract: Cancer stem cells (CSCs) are a subpopulation of tumor cells with properties of self-renewal, pluripotency, plasticity, and differentiation, and are associated with various aberrantly stimulated signaling pathways. They are responsible for tumor recurrence, distant metastasis, and drug resistance, thus inducing poor prognosis. Immunotherapy has achieved en...

Abstract: Background:  Both of UFT-/Tegafur-based postoperative chemotherapy and postoperative radiotherapy have made large progress in treatment of early-stage non-small cell lung cancer. While it is unclear that, whether UFT-/Tegafur-based postoperative chemotherapy is superior to postoperative radiotherapy for early-stage non-small cell lung canc...

Abstract: Polymerase-tautomeric model for   untargeted delayed base substitution mutations is proposed. Structural analysis of bases insertion showed that any canonical bases may be inserted opposite rare tautomeric forms of thymine T 3 *, adenines A 2 * and A 4 * so that between them hydrogen bonds are formed. Canonical ad...

Abstract: About 15.4% of human cancers worldwide have been attributed to infections. Among these, blood and liver flukes, notably Schistosoma  sp, Clonorchis Sinesis,  and  Opisthorchis Viverrini  have been associated with the development of various cancer types. Schistosoma  sp. promotes colorectal cancer (CRC) progression through mu...