Table of Contents


Yunbo Zhang, Liping Zheng, Junqi Liu, Jinqiu Li, Jianguang Zhang, Jingjing Ma, Yuxiu Song

Article ID: 3513
Views - 204  (Abstract) PDF - 53  (Download)
Abstract:The purpose of this study is to clarify the significance of postoperative radiotherapy for N2 lung cancer. This study aimed to investigate the effect of postoperative radiotherapy on the survival and prognosis of patients with N2 lung cancer. Data from 12,000 patients with N2 lung cancer were extracted from the Surveillance, Epidemiology, and End Results dat...
I. Gin, I. Chistyakova, V. Zenin, S. Koshkin, A. Musorina, Y. Lahina, G. Timin, V. Pospelov, S. Prikhodko, A. Petukhov, E. Tolkunova

Article ID: 3566
Views - 199  (Abstract) PDF - 55  (Download)
Abstract:Gliomas are solid brain tumors composed of tumor cells and recruited heterogenic stromal components. The study of the interactions between the perivascular niche and its surrounding cells is of great value in unraveling mechanisms of drug resistance in malignant gliomas. In this study, we isolated the stromal diploid cell population from oligodendroglioma an...
U. Rilwan, A. Hudu, A. Ubaidullah, A. U. Maisalatee, A. A. Bello, E. I. Ugwu, G. O. Okara

Article ID: 3633
Views - 142  (Abstract) PDF - 51  (Download)
Abstract: A survey of Fertility Cancer and Hereditary Risks in Soil Sample of Nasarawa was carried out. This study assessed the level of Fertility Cancer and Hereditary Risks in some part of Nasarawa using the gamma-ray spectrometry. The mean concentration for 40 K was 645.29 ± 07.32 Bq/kg, for 226 Ra was 28.43 ± 4.8422 Bq/Kg and...
Aditi Mittal, Kanu Neemawat, Sandeep Jasuja, Anushree Chaturvedi

Article ID: 3645
Views - 157  (Abstract) PDF - 36  (Download)
Abstract:Cancer is a leading cause of death for children and adolescent worldwide. The cure rates in low middle-income countries are dismal (20%) in comparison to high income countries (80%). The first move is to assemble precise data on epidemiology of pediatric cancer across the country and its region wide variation. This study attempts to provide spectrum of pedia...
Lisiane Silveira Zavalhia, Andrea Pires Souto Damin, Grasiela Agnes, Aline Weber, Taís Frederes Kramer Alcalde, Laura Marinho Dorneles, Guilherme Watte, Adriana Vial Roehe

Article ID: 3632
Views - 125  (Abstract) PDF - 51  (Download)
Abstract: The loss of heterozygosity (LOH) is a genetic event that can change gene function.  FHIT  is a potential tumor suppressor gene.  Although the precise FHIT molecular mechanism of action is not well understood, evidences suggest that Fhit protein reduced levels are involved in mammary carcinogenesis.  The aim of this study was to investigate if  F...
Alexander Aizikovich

Article ID: 3629
Views - 183  (Abstract) PDF - 46  (Download)
Abstract:The in vitro study of tetracannabinolic acid (THCA) derivatives ALAM027 and ALAM108 was carried out on the following human tumor cells: T47D (breast, ductal carcinoma), PC-3 (prostate, adenocarcinoma), HT29 (colorectal carcinoma), Caco-2 (colon, adenocarcinoma), A549 (lung, carcinoma), U87MG (human glioblastoma) and U266B1 (multiple myeloma). The in vitro ef...
Daniela Kristina D. Carolino, Edwin Joseph R. Guerzon, Richard S. Rotor

Article ID: 3669
Views - 124  (Abstract) PDF - 32  (Download)
Abstract:Giant cell tumor of the bone (GCTB) is a benign, locally aggressive neoplasm that is relatively rare, with a propensity to result in progressive bone destruction, and is associated with a high risk of recurrence. There is no widely held consensus regarding its ideal treatment. Worldwide, there are varying techniques ranging from intralesional curettage to re...


Avik Mandal

Article ID: 3646
Views - 127  (Abstract) PDF - 37  (Download)
Abstract: Pancreatic adenocarcinoma (PAC) is an extremely fatal malignancy with dismal outcome with standard treatment till date. Investigators are constantly in search of optimal treatment approach and radiation therapy (RT) remains in the centre of debate. Human pancreatic cancer cell lines have shown both intrinsic and hypoxia induced radio resistance, and RT ha...
Tomas Koltai

Article ID: 3649
Views - 157  (Abstract) PDF - 40  (Download)
Abstract: Dose is one of the parameters that any pharmacologist seriously considers when studying the effects of a drug. If the necessary dose to achieve a desired pharmacological effect is in a toxic or very toxic range for human use, the drug will probably fall out from further research. The concentration that a drug can reach at its target organ or cell is a dir...